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An adrenoceptor is another name for an adrenergic receptor.
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What has the author Alex Duncan McCormick written?
Alex Duncan McCormick has written: 'The beta-adrenoceptor antagonist ICI 118,551'
What has the author Patricia Marian McCaffrey written?
Patricia Marian McCaffrey has written: 'Studies of agonist and partial agonist activity at the beta-adrenoceptor in man'
What has the author James Gray Riddell written?
James Gray Riddell has written: 'Studies of the disposition, actions and excretion of beta-adrenoceptor blocking drugs'
What has the author Peter John Beckett written?
Peter John Beckett has written: 'Central cardiovascular and peripheral alpha-1 and alpha-2 adrenoceptor activity of some antihypertensive agents'
What is the active ingredient listed on the Precedex package insert?
Alpha 2 adrenocepter is the active ingredient for sedation listed on the Precedex package insert. "The Precedex package insert says the drug is used for sedation, and claims it is an alpha 2 adrenoceptor."
What has the author A Pearson written?
A. Pearson has written: 'Life is in charge' 'Determination and comparison of the pA2 values of certain a2-adrenoceptor antagonists using isolated prostatic portions of rat vas deferens'
How are beta-adrenoceptor blockers used to treat heart failure?
Beta blockers can decrease the myocardial contractility and make heart failure worse. However, beta-blockers were shown to reduce mortality and morbidity in heart failure patients. This may be due to how they can block the damaging effects of sympathetic activity which is too active. Usually, beta-1 selective blockers such as carvedilol are used. Beta blockers should be used in all patients with stable heart failure with reduced LVEF. They should be used after ACE inhibitors.
What causes lid lag in hypothyroidism?
Firstly lid lag is found in HYPERthyroidism, not hypo. The explanation for this is as follows: If you (a normal person) takes an overdose of thyroxine, you would get lid lag, but not exophthalmos. This is because thyroxine is a beta adrenoceptor sensitiser. Thus the beta receptors in your heart are more active as adrenaline levels rise. Similarly, the beta receptors in levator palpabrae superioris (the muscles that open the eye) are more sensitive, and hold your eyes open. You will remember from Anatomy that the nerve supply to that muscle is half from the third nerve (occulomotor) and half from the sympathetic chain. This is the opposite of what happens when you cut the sympathetic chain (as in Horner's syndrome) when the eye will partly close.
How can a beta-adrenoreceptor blocker be used to treat high blood pressure?
The beta-adrenoceptor blockers block both beta 1 and beta 2 adrenoceptors. The blockage of beta 1 adrenoceptors results in a decreased heart rate and contractility. The cardiac output will hence be reduced leading to the blood pressure being lowered. In addition, the beta-adrenoceptors also act on the beta 1 adrenoceptors of the kidney. It leads to plasma renin activity being supressed so that less angiotensin II is formed. Angiotensin II is a vasoconstrictor itself and it can also induce the release of the antidiruetic hormone and aldosterone which contributes towards the blood pressure being increased.
What is vasoconstriction and is there a treatment?
Answervasoconstriction is when some blood vessels (arteries, arterioles, etc) constrict and essentially increase the impedance to blood flow. This is known as vascular resistance, and is a major contributor to blood pressure (hypertension).Blood vessels are usually in a state of relative constriction, but can constrict further in respone to cold (thermoregulation), to low blod volume or low blood pressure (shock/maintaining a normotensive state/maintaining perfusion pressure) or to signals from the nervous system, which can be replicated by the administration of drugs (e.g. adrenalin).Treatment for vasoconstriction would include the use of vasodilators- alpha adrenoceptor antagonists, or calcium-channel blockers. The latter group of drugs is often used in the treatment of hypertension.
What are some animals that begin with the letter Y African?
Some places in Africa starting with Y are:Yaounde, CameroonYamoussoukro, Ivory CoastYangambi, Democratic Republic of the CongoYelimane, Republic of MaliYosemite National Park, South Africa
What are the functions of salbutamol?
Salbutamol is a beta 2 adrenoceptor agonist. It binds therefore to Beta 2 receptors found particularly in the bronchioles of the respiratory system. In binding to these receptors it activates the Gs protein that the receptor is associated with and GDP is exchanged for GTP. This then activates the enzyme adenylate cyclase that coverts ATP into cAMP (a secondary messenger). Increased intracellular cyclic AMP (cAMP) increases the activity of cAMP dependent protein kinase A, which alters the phosphorylation of myosin and lowers intracellular calcium levels within the muscle. Lower levels of calcium cause relaxation of the smooth muscle and therefore bronchodilatation. Bingo! The airways dilate and everyones happy!
