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I am guessing that the interchange is that one in 2,2 as follows:

Lady M: Did you not speak?

Macbeth: When?

Lady M: Now.

Macbeth: As I descended?

Lady M: Ay.

Macbeth Hark! Who lies in the second chamber?

Lady M: Donalbain.

Macbeth: This is a sorry sight.

The conversation is usually performed very rapidly with the words almost tumbling over each other. The characters are trying to answer each other but Macbeth is distracted by his own thoughts. Lady M has heard a voice, and wants to find out about it, but she never gets an answer. Macbeth asks who is sleeping in Room 210, but when he gets his answer he does not explain why he asked it but goes on to talk about his bloody hands. They are nervous, their thoughts (and we assume their hearts) are racing to the extent that they are incoherent. Their nervous tension gets communicated to the audience.

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10y ago
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7y ago

Up until the murder Lady Macbeth was in charge. Afterwards, Macbeth was in charge.

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Q: What is the shift between Macbeth and lady Macbeth?
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