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Federalism impacts the performance of the FDA by establishing a division of responsibilities between state and federal governments, which can create both collaboration and conflict. While the FDA sets nationwide standards for food and drug safety, states may have their own regulations that can either complement or complicate federal efforts. This dual system can lead to inconsistencies in enforcement and compliance, affecting public health outcomes. Additionally, the FDA must navigate varying state laws and priorities, which can complicate its regulatory processes and decision-making.

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