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Yes and no. There are two levels of leadership, state and federal. On the state level the leadership takes away offices, parking spots and committee appointments. In CA they have been known to move a person from a plush office to a basement cubby. One fellow had a desk in a hallway in the basement. On the national stage they are a bit more subtle, but the effect is the same. Often a person who is running for their office again won't get support from the national party or committees they can use to rise in leadership. So,yes they are punished for not towing the line and unless they fall into place they are exiled resulting in pressure to quit.

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