How does a neuromuscular blocker drug work?

Answer 1

Neuromuscular blockers work by interfering with the transmission of signals between nerves and muscles. They achieve this by either blocking the action of acetylcholine at the neuromuscular junction (competitive antagonists) or by causing a persistent depolarization of the muscle membrane (depolarizing agents). This prevents muscle contraction, leading to temporary paralysis, which is useful during surgical procedures or in certain medical conditions. The effects of neuromuscular blockers are reversible, allowing for muscle function to return after the drug is cleared from the system.