That would depend upon the location of your city of departure. The Vatican does not have an airport so all visitors to the Vatican who arrive by plane do so through Rome's International Airport.
The Vatican is totally surrounded by the city of Rome. Take one step outside the Vatican and you are in Rome.
The Vatican City is very close to Rome, Italy. It only takes 11 minutes to get there on an average day with a maximum of usually 15-20 minutes.
About 4 hours pending on the city.
about 4 hours for a nonstop
That depends on where you are flying FROM.
0 miles - if you take one tiny step out of the Vatican, you are in the city of Rome.
Vatican Council II (1962 - 1965) was held in Vatican City located in Rome, Italy.
By plane, it would take about 5 hours.
about 6 hours
4 hours
Unless the plane wants to take the long way around... the plane would fly west.
Vatican City is an independent country - a city state - surrounded by the Italian city of Rome. Once a person arrives in the city of Rome, he need only take a taxi, metro or bus ride to the Vatican and simply walk across the border.