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Dr. Houses leg had mussle death due to an infarction during surgery. He was going to have it amputated but stibornly refused to have his leg emoved despite the large amount of pain he was in. He went into complex white attack acardia and was technichally dead for over a minute. He then asked to be put in a chemicaly induced coma. They (the doctors) went in surgicly and removed the dead mussle. This was all when he was still with Stacy. In the end, his leg was ok and alive but he walks with a limp for all his life and is constintly in pain. He's addicted to pain pills, Vicodin, and in series 7 he went to rehab. He is now off Vicodin.
He revealed all this in series 1 episode 21 'three stories' during a medical lesson to students.
Hope this helped
MonkeyLover-Dinda
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