Mafia

Yes, Tony Soprano killed his nephew, Christopher Moltisanti, after many twists and turns over the years. Christopher was always a "loose cannon" as they say, and despite his becoming a "made man" and a capo over the years, he also struggled with drug addiction. Even though Christopher told Tony upon learning that his longtime girlfriend, Adriana, was an FBI informant (she was soon killed on Tony's orders), it seemed that Tony never fully trusted Christopher after that. His murder of Christopher seemed to be caused by a combination of mistrust and disgust over Christopher's many transgressions and mistakes over the years (against Tony, the "family," and others).

In the book Fabrizio is murdered on the day of the famous baptism scene there was a spot in the movie where Michael puts on a white fedora and kills him with a shotgun, but that was deleted. In the second movie he is killed by a car bomb which was the same way he killed Apollonia but that scene was deleted as well. So he was never truly killed in the movie.