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On Amazon it was rated 1 star in 12 out of 22 ratings.

It is not listed on the actual FDA web site. Although they say they are recognized by the FDA, their own web site has the disclaimer, "These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, or prevent any disease."

The main active ingredient is vincamine, which is from the periwinkle flower. In a report submitted to the FDA, there were reports of some toxic effects when tested on animals.

It also stated that there is inadequate information to provide reasonable assurance

that the new dietary ingredient does not present a significant or unreasonable risk of illness or injury.

See the related link for the full original report on the FDA web site.

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