A perpetual motion machine of the second kind (PMM2) is impossible according to the second law of thermodynamics, which states that heat cannot spontaneously flow from a colder body to a hotter body without external work. PMM2 would violate this principle by converting thermal energy from a heat reservoir into work without any loss, effectively creating energy from nothing. This contradicts the concept of entropy, which dictates that in any energy exchange, the total entropy of a system and its surroundings will either increase or remain constant, but never decrease. Thus, such a machine cannot exist.
WHAT IS PMM-1 A PMM1 is a Thermodynamic system that undergoes a cyclic process that produce no external affects other than the rise ( or fall) of a weight in a gravity field. WHY IS IT IMPOSSIBLE? PMM-1 state that work can still be produce in a cyclic process. This definition is against first law of thermodynamics and conservation of energy. According to first law of thermodynamics, in cyclic process E2- E1 = mg (h2 - h1) h2= h1 in cyclic process so the above equation yields E2=E1. where as according to PMM-1 you can produce work even when energy is zero (0), which makes it impossible
Defective Enzyme Disorder: includes the following: α-Mannosidosis α-Mannosidase β-Mannosidosis β-Mannosidase α-Fucosidosis α-Fucosidase Sialidosis α-Neuraminidase Galactosialidosis Protective protein Aspartylglucosaminuria Aspartylglycosaminidase Schindler disease α-N-Ac-galactosaminidase Mucolipidosis II (I-cell disease) N-acetylglycosmaine-1 phosphotransferase Mucolipidosis III N-acetylglycosmaine-1- phosphotransferase.