read it:)
Possible activation of several different second messenger systems.
"Messenger".
Arginine
inositol triphosphateInositol triphosphate (IP3) and diacylglycerol (DAG) are important second messengers. Their formation begins with the binding of an extracellular regulatory
The first messenger is nothing but referred to the molecule that brings information upto the cell surface. Once this molecule transfers signal to cell, it is taken over by the well known second messenger to take it further to nucleus through various other signaling molecules down the cascade.
The suicide of Jocasta, Oedipus' wife.
Protein kinase A is activated by the second messenger through a process called phosphorylation. When the second messenger binds to the regulatory subunit of protein kinase A, it causes a conformational change that releases the catalytic subunit. This released catalytic subunit is then able to phosphorylate target proteins, leading to various cellular responses.
A neurotransmitter whose function depends on a second messenger is known as a neuromodulator. Neuromodulators can influence the behavior of neurons by affecting processes like signal transduction or synaptic transmission.
Peptide hormones bind to cell surface receptors, activating signaling pathways that involve the generation of second messengers within the cell. The first messenger (peptide hormone) triggers the activation of specific proteins or enzymes that then generate the second messenger molecules, such as cyclic adenosine monophosphate (cAMP) or inositol trisphosphate (IP3), initiating a cascade of cellular responses.
Testosterone does not act on a second messenger system. Testosterone acts directly on genes within a cell to initiate cellular changes, whereas the other hormones listed (Glycogen, Epinephrine, Growth Hormone, ACTH) typically use second messenger systems to transmit their signals inside the cell.
if you want to get rid of the messenger lock you can go to the top of the msn page and press the Plus! button then click on preferences and options. Click on the second tab messenger and on the left side it says "messenger lock",click on that and deactivate it by undoing the active messenger lock. Press apply and then ok. Hope this helps, best regards, Slurpeekid:D