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The active drug in cigarettes is nicotine. As a stimulant, nicotine produces wakefulness and alertness. However, due to its addictive properties, tolerance and dependence accrue farily quickly. Thus, withdrawal symptoms occur, often just minutes after the previously inhaled dose, and these symptoms include anxiety, motor tension, fatigue and irritability, among others. In the process of treating withdrawal syymptoms by lighting up the next cigarette, relief is obtained. Paradoxically, this accounts for the sense of calm experienced by the smoker, while using products which contain nictoine, a stimulant.

Cigarettes also contain hundreds of other ingredients, including tar, carbon monoxide and other chemical toxins. Tar (and other substances) gradually destroys the cilia (wavy hairs) of the respiratory tract, and eventually destroys lung cells, as well, setting the stage for COPD (chronic obstructive pulmonary disease). Also, carcinogens in cigarette smoke predispose the user to cancer,, increasingly over time. Also, smoking contributes to coronary artery disease and places the user at increased risk of heart attacks and strokes.

Since one quarter of the populace smokes cigarettes, it is considered a major public health hazard, secondary smoke notwithstanding. It is one of the top preventable causes of heart disease, cancer, strokes and respiratory diseases (which make up the leading causes of death in the U.S.).

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