How far from Chicago to Daytona Beach?

Answer 1

1. Take I-65 SOUTH to I-865 EAST TO I-465 EAST at EXIT 129.
2. Take I-865 EAST to I-465 EAST. Then take I-465 around Indianapolis to I-74 EAST to CINCINNATI at EXIT 49.
3. Take I-74 EAST to I-275 SOUTH towards Kentucky at EXIT 5 in Ohio outside of Cincinnati.
4. Take I-275 around Cincinnati to I-75 SOUTH at EXIT 84 in northern Kentucky.
5. Take I-75 SOUTH all the way down to I-10 to JACKSONVILLE and TALLAHASSEE at EXIT 435 in Florida. Follow signs to I-10 EAST to JACKSONVILLE. On I-75 you will bypass three cities: first you will bypass Knoxville, Tennessee via I-640/75. Second, you will bypass Atlanta, Georgia via I-285 WEST BYPASS. (EXIT 259 off I-75, then EXIT 58 off I-285 to get back onto I-75 SOUTH). Third and finally, you will bypass Macon, Georgia via I-475 SOUTH (EXIT 177 off I-75).
6. Take I-10 EAST to I-295 to INT'L AIRPORT SAVANNAH and ST. AUGUSTINE. You want I-295 SOUTH to ST. AUGUSTINE and ORANGE PARK.
7. Take I-295 around Jacksonville to I-95 SOUTH to Daytona Beach at EXIT 61A.
8. Take I-95 SOUTH to Daytona Beach.

Answer 2

Here are the results I was able to get from MapQuest.com

Total Travel Estimate: 18 hours 17 minutes / 1155.93 miles