No it is not true the region between the Appalachian mountains and Mississippi river is called the Northwest Ordinance.
the mississippi drainage basin is located between the Appalachian Mountains and the Rocky Mountains
The United States of America
The Great Plains, the Mississippi River system, and the eastern woodlands all lie between the Rocky Mountains and the Appalachian Mountains.
the wilderness path
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The Appalachian Mountains and the Mississippi river ,:L<":< ;Lemuel's
it was Randy Putrus
George Rogers Clark
The land between the Appalachian Mountains and the Mississippi river was called the Louisiana Purchase after the Revolutionary War. The Louisiana Purchase was 530,000,000 acres of territory in North America that the United States purchased from France in 1803 for $15 million.
somoene answer it
The Great Plains is the huge expanse of flatlands from the Rocky Mountains eastward to the Mississippi River.
The Appalachian Mountains are between Georgia and New York.