St.Lawrence River
The Ohio River
The Ohio River
for trade and transportation
There are thousands of towns west of the Appalachians.
The Ohio River forms the boundary between Indiana and Kentucky.
American Indians controlled the land west of the Appalachians.
Early Americans thought of the Area between the Appalachians and the Mississippi River as the western frontier.
The Ohio River
The Ohio River is found west of the Appalachian Mountains. It forms a border between Indiana and Kentucky, as well as between some other states.
Settlement had begun in the Ohio River Valley as well as the Mississippi River Valley. Exploration and rising tensions with American Indians had also begun.
Appalachians
Early Americans thought of the Area between the Appalachians and the Mississippi River as the western frontier.