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To effectively manage and utilize poison counters in a Commander game, focus on cards that can give your opponents poison counters, protect yourself from receiving them, and win the game by reaching the required number of poison counters. Use cards like Tainted Strike to give your creatures infect, and cards like Melira, Sylvok Outcast to prevent you from getting poison counters. Keep track of the number of poison counters on each player and strategize to reach the necessary amount to win.

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5mo ago

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