sky,fly,fry, do not have vowels
cauliflower
authoreiaetian
The instrument that contains all the vowels is the "accordion." The word "accordion" includes the vowels A, E, I, O, and U. This makes it a unique example among musical instruments.
sequoia
Quatrefoil
The word "stomach" contains two vowels - 'o' and 'a'.
The word that contains all the vowels is "euouae." It is a musical term used in medieval music, specifically in Gregorian chant notation.
The 8-letter word that contains four 'N's and the other four letters are all vowels is "announcer."
Without vowels, you can't pronounce the words. Try to pronounce frnc. It is furnace or franc without the vowels.
You may be going for the fact that it contains all of the vowels, but it is not the only such word. Facetiously contains them all, plus "y" (and in alpha order, to boot).
Abstemious is a 10 letter word that contains 5 vowels in correct order. It means not moderate when eating and drinking.
Rhythms is a seven letter word that contains no vowels.