Words with IE in the middle:dieddiesdietliedliespierpiespriesttiedtierties
sauce
OMELETTE
Words with "te" in the middle:litersmeters
Some six letter words with FF in the middle are:wafflebafflebufferduffermufflepifflesufferduffelpuffindiffer
Some words that have the letters ME twice in the middle are:amendmentcommencementdismembermentmeantimemeasurementmementomerrimentmesmerisemetronomesometimesummertime
Cobra
Year 1000 was approximately in the middle of the Middle Ages
Some six letter words with OOS in the middle:IgloosKazoosWazoosYahoos
bookboombootcookcoolcoopcootdoorgoodgoongoophoodhookhooplookloonloomlooplootmoodmoonmoornookpoofpoorpoolrootrookroofroomsoonsoottoottooktoolwoodwoolwoofzoom
A real word is trekker, a slang word is likker.
Words that have "sp" in the middle include "aspirate," "displace," "despair," and "raspberry." These words feature the "sp" combination between other letters, creating various meanings and contexts.