Which airport?
From Colon to the domestic airport 40 minutes.
From Colon to Tocumen (PTY) an hour and a half, depending on traffic.
This would be taking the toll road.
it is appx a 2 hr 2 1/2 drive from Panama city to Colon, that would be from Pacific ocean to the Atlantic.
You are better off to take the bus. It's a smooth ride, costs $4 for the express bus, and at the Panama City bus station, there are plenty of taxis to take you to Tocumen Airport. The cost for the taxi will be about $25. If you are flying out of the Albrook Airport (the one for Panama travel), you will already be there. The bus station is part of the airport. My husband and I caught a ride from Colon to Panama City with someone who was going there anyway, and it was $50. A taxi would be more.
Balboa and Colon are two cities in Panama besides Panama City
Colon.
The distance between Tallahassee Regional Airport and Panama City, FL is 95.6 miles and will take about 2 Hours 5 Minutes to drive.
46 miles
The closest major airport to Panama City, Florida is Northwest Florida Beaches International Airport (ECP / KECP). This airport is in Panama City Beach, Florida and is about 15 miles from the center of Panama City, FL.
Paitilla International Airport. PTY.
I am not sure exactly but it was about a three hour drive for us
Panama City Florida is approximately 120 miles away from Pensacola airport, which is about a 2-hour drive.
Panama City Colon David
on the eastern (Atlantic/Caribbean) coast of Panama. .. the eastern end of the Panama Canal