2 business days
Google Maps estimates the driving time as 3 hours and 14 minutes.
45minues
about like 9 hours
about 4 hours
If you take I-40W then it is approximately 2,143 km, 22 hours.
To get to the Mississippi River from Meridian, MS, you simply take Interstate 20 through Jackson, MS to Vicksburg, MS. Once entering Vicksburg, continuing on Interstate 20 crosses the Mississippi River. Another route is to use Interstate 20 to Jackson, MS. continue to the Natchez Trace and continue to Natchez, MS. It "dead" ends at the Mississippi River.
3 hours
The distance between Tyler, TX and Shreveport, LA, is 97.2 miles and will take about 1 Hours 35 Minutes of driving time.
It will probably take about 1 to 2 hour or maybe less then that.
4 hours and 18 minutes
The flight time is 1 hour, 35 minutes.