How many miles from St. Louis MO to Columbia SC?

Answer 1

The driving distance is 125 miles. Since there is sometimes more than one route, including back roads, this is an approximate but accurate distance. It is based on the most well-known routes between these two locations.

Answer 2

17 miles taking this route:

1. Take I-270 NORTH from Des Peres to I-64 EAST to St. Louis at EXIT 12.
2. Take I-64 EAST to St. Louis.

Answer 3

The driving distance is about 960 miles.

Answer 4

The driving distance is about 170 miles.

Answer 5

It is 749 miles according to Google Maps.