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The easiest route to drive from Syracuse, NY, to Naples, FL, is to take I-81 South to I-77 South, then merge onto I-26 East, and finally connect to I-75 South, which will lead you directly to Naples. This route covers approximately 1,200 miles and typically takes around 18-20 hours of driving time, depending on traffic and road conditions. It's advisable to plan for rest stops along the way to ensure a comfortable journey.

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2mo ago

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