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The fastest route from Reno, Nevada, to Jacksonville, Florida, typically involves taking I-80 East to I-15 South, then merging onto I-40 East. From there, you would continue on I-40 until reaching I-75 South, which leads directly into Jacksonville. The total driving distance is approximately 2,500 miles and may take around 36 to 40 hours of driving time, depending on traffic and road conditions. Always check for real-time navigation updates to optimize your journey.

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1w ago

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