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Amerigo Vespucci was a Florentine merchant and navigator who made at least two transatlantic trips to the New World, voyages that inspired cartographer Martin Wardseemüller to label the new continent "America" in 1507.

http://www.answers.com/Amerigo%20Vespucci%20

Hernando De Soto

Spanish explorer ~1500 - 1542

De Soto was born in the province of Extremadura in Spain. As a teen-ager, he sailed to the New World and began his career as an explorer in the tropical rain forests of Panama. De Soto served in expeditions to enslave Indians and to search for wealth. By the early 1530's, de Soto was known as an excellent soldier and horseman. He joined an expedition led by Francisco Pizarro, another Spanish explorer, against the empire of the Inca Indians in what is now Peru. After a short delay, the men began their journey in 1532 with a small army of 168 men. They reached the city of Cajamarca, where a huge Inca army, commanded by Emperor Atahualpa, was camped.

http://www.laughtergenealogy.com/bin/histprof/misc/desoto.html

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