Amerigo Vespucci was a Florentine merchant and navigator who made at least two transatlantic trips to the New World, voyages that inspired cartographer Martin Wardseemüller to label the new continent "America" in 1507.
http://www.answers.com/Amerigo%20Vespucci%20
Hernando De Soto
Spanish explorer ~1500 - 1542
De Soto was born in the province of Extremadura in Spain. As a teen-ager, he sailed to the New World and began his career as an explorer in the tropical rain forests of Panama. De Soto served in expeditions to enslave Indians and to search for wealth. By the early 1530's, de Soto was known as an excellent soldier and horseman. He joined an expedition led by Francisco Pizarro, another Spanish explorer, against the empire of the Inca Indians in what is now Peru. After a short delay, the men began their journey in 1532 with a small army of 168 men. They reached the city of Cajamarca, where a huge Inca army, commanded by Emperor Atahualpa, was camped.
http://www.laughtergenealogy.com/bin/histprof/misc/desoto.html
Cortes found the Aztec civilization in the present-day Mexico region
Hernan Cortes is a Spanish explorer known for conquering the Aztec Empire in Mexico.
Hernan Cortes
Garcia Lopez
One famous Spanish explorer is Hernán Cortés. He is known for conquering the Aztec Empire in Mexico in the 16th century.
Hernán Cortés is the Spanish explorer who encountered the Aztec Indians who were using cocoa beans. He first encountered the Aztecs in 1519 during his conquest of Mexico.
Hernando de Soto
Zebulon pike
One extremely important Spanish explorer and conquistador, named Hernando Cortes, explored a good part of modern day Mexico.
Hernan Cortez conquered the Aztec Empire.
The most important among them would be Hernan Cortes (1485-1547): First discoverer of Mexico; he conquered the whole region for the Spanish Empire and set four expeditions to northwestern Mexico. He is the discoverer of the Baja California Peninsula.
Florida was discovered by Spanish explorer Juan Ponce de Leon (1474 - 1521), while Mexico was discovered by Spanish conquistador Hernan Cortes (1485 - 1547).