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The best route to drive from Orlando, Florida, to the Kentucky Derby in Louisville, Kentucky, typically involves taking I-75 N. Start by heading north on Florida's Turnpike, then merge onto I-75 N, which you will follow through Georgia and into Kentucky. As you approach Louisville, take I-65 N, which will lead you directly to the city and the Derby venue. This route is approximately 700 miles and usually takes around 10-11 hours, depending on traffic and road conditions.

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2mo ago

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