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The conflict between northern and southern states in the U.S. primarily centered on issues of slavery, states' rights, and economic differences. The North, which was more industrialized and favored free labor, sought to limit the expansion of slavery into new territories. In contrast, the South's economy relied heavily on agriculture and enslaved labor, leading them to advocate for the preservation and expansion of slavery. This tension ultimately culminated in the Civil War, as both regions struggled over the moral and political implications of slavery and federal authority.

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