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The Huron tribe were their greatest enemy, taking extreme measures to fight the Seneca.

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Wiki User

10y ago
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Wiki User

11y ago

It was the english

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Wiki User

15y ago

the french.

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Wiki User

10y ago

Sioux

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Anonymous

Lvl 1
3y ago

The main enemy of the Seneca tribe was the Huron/Wyandot. The Seneca eventually defeated them by surrounding them when they were weakened by severe smallpox cases. The Huron surrendered and they pledged allegiance to the Seneca as their protector.

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Q: Who were the enemies of the Seneca tribe?
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