How can you dissolve trimethoprim?

Answer 1

The easiest way to dissolve trimethoprim for oral administration is to drop the tablets into a 60cc syringe - pull the plunger out then drop the tablets into the body of the syringe. Put the plunger back in and depress it until the tablets can't rattle around. Fill a small glass with tap water, then pull water into the syringe. Place a fingertip over the tip of the syringe to seal it, then shake the syringe to get the tablets to dissolve. This may take a few minutes, and the resulting paste/gel/liquid is not going to taste good to your pet so expect to need some help restraining him/her to give the medication.