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it is a mathematical formula based on the halfe life of maternally derived antibodies. it is used to estimate the optimal age of infectious bursal disease, an avian viral pathology, which leads to immunodepressoin in chickens.

The Deventer formula is as follows:

Vaccination age = { (log2 titre bird% - log2 breakthrough) x t1/2 } + age at sampling + correction 0-4

In which

Bird% = ELISA titre of the bird representing a certain percentage of the flock

breakthrough = breakthrough (ELISA) titre of the vaccine to be used

t1/2 = half-life time (ELISA) of the antibodies in the type of chickens being sampled

Age at sampling = age of the birds at sampling

Correction 0-4 = extra days when the sampling was done at 0 to 4 days of age.

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