Hey Man, Your problem will be one them as the link below theare are solution of all the problem which you are facing while installing Prototype 2 even my one is their so i solved them.
Please check related link below
Change the compatibility mode of the program to Windows 98/Me
If you just logged on, you will see a welcome screen, and possibly your desktop and icons.
One potential solution for fixing computer crashes from the Amazing Spiderman game is ensure the drivers are updated for the game. Also, disabling any anti-virus software before playing the game is another potential solution to try out.
On my MAC I go to System Preferences and then into desktop. At that point I choose a new picture for my screen. A similar command exists under Windows but I forgot what it is. I do not have my manual with me.
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your game is broken you have to get a new spiderman.
Check that the cable for your monitor is correctly inserted into the computer and into the monitor, and is turned on.
This may be occur because your Graphics card is not supported or may be any resolution problem.
the black box
It depends on if you're talking about the background of your desktop or the background of a running program. FOR DESKTOP. Rightclick desktop, properties, desktop, make background picture None and change the color to black. FOR PROGRAMS. Rightclick desktop, properties appearance, advanced, window, then change that to black and the font color to something like white or whatever, something you can see on top of black.
resolution is 600 x 800, black wallpaper, and "Safe Mode" will be in all four corners of the screen
Reinstall windows.