How do you beat silitha on darksiders?

Answer 1

Hold the left trigger down to keep camera focus on her. When she finishes teleporting, use the grapple chain to pull yourself up into the air near her, this is where you should get your attacks in. Then keep dodging randomly as she tries to attack you, repeat this cycle.

After she takes enough damage, she'll teleport around you rapidly until she halts and attacks. Again, keep dodging around the room.

Eventually she will crawl to the ceiling and summon a ring of floating explosives. When these turn orange, you can grapple up to one of them, then grapple onto Silitha herself. She will be slain in the following cutscene.