P.S.: It's easier to kill him in co-op mode.
When he appears, Sheva and Chris must run in the opposite side. There will be a cinematic where Chriss falls. Wesker will go to Chriss. Chriss must go on the island and shoot at Wesker with explosives or a magnum. Sheva must shoot in Wesker's back with a sniper rifle. Wesker will jump to Sheva. Sheva must run in the oposite side. There will be a cinematic where she falls and hang on a rock. Sheva must press "x" as fast as she can. Chriss must shoot Wesker to give sheva some time. (it's better with a sniper rifle.) Sheva will climb the rock after a few seconds (30 seconds maybe). Chriss must go to a big rock and push it. To stop Wesker, Sheva must shoot at him with a powerfull weapon. When Chriss succeed, Sheva must rejoin Chriss on the island. Wesker will go to the island. Chriss and Sheva must shoot at his back or his torso (there should be an orange weak spot) After some time, the spot will disapear and Wesker will do a "super-attack". Sheva and Chriss must go away from Wesker. When he finishes his attack, the weak spot will appear again. Sheva and Chriss must shoot at this weak spot and Wesker will die.
Remind me which boss? What does he look like
beat the mines stage with an A you get midnight wesker you beat the prison stage with an A you get Wesker S.T.A.R.S from jamie wyvill
All you have to do is beat every chapter on hard, Not including operation Javior 6,7 (Krauser's mission's)
To beat Krauser in Resident evil 4 you need to keep shooting with your magnum.But unsing your knife when he is on his knees is okay too.
play it
beat all the scenarios including decisions decisions, then you've did it
beat the main game
beat the game on normal
beat the hole game
beat the game in 5 hours
You got to be quick on your feet
Beat the game first