In "Marvel: Ultimate Alliance," MODOK (Mental Organism Designed Only for Killing) serves as a villain and a boss character. His answers and dialogue often reflect his egotistical and villainous nature, showcasing his intelligence and disdain for others. He frequently expresses his desire for power and control, as well as his contempt for heroes, emphasizing his belief in his own superiority. Players encounter MODOK primarily in the context of his plans involving the Cosmic Cube and his attempts to dominate the world.