Pull the trigger.
No.
No, you cannot.
Can I shoot 380acp caliber out of my 32 pistol?
Yes.
500 m or so IIRC
If you shoot enough of them you get the punisher handgun for free from the merchant.
Yes you can. The bore is the same size.
Single shot 50 BMG Yes, that would work. You can shoot one with whatever handgun you wish to use. Just be sure you can run faster than whichever bear you pick to shoot if you pick a caliber that does not kill it.
DO NOT ATTEMPT THIS!!. Never fire ammunition in a weapon that it is not chambered for.
It depends on the model, but most handguns are meant for short to medium range conflict.
Yes, a .44 caliber Derringer I believe.
Well, this is going to sound like a smart-ass answer, but it isn't. You can shoot any handgun or firearm accurately by properly aligning the sights and pressing the trigger correctly. If you are having trouble with accuracy, you are almost positively doing one of those things incorrectly.