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There are all sorts of answers to this question. If you ask 10 people that claim to be experts, you will get at least 4 or 5 different answers, and every person will claim that his answer is the best. In general, any caliber that has enough penetration that you can shoot accurately is the best choice. Many people will tell you that shot placement is the only important factor, but they fail to realize that shot placement without accurate penetration doesn't do much for you. If you get a good, solid, upper center chest shot from a low powered gun but the bullet doesn't penetrate deep enough to hit a vital organ, you haven't accomplished much. Many people believe that 9mm parabellum is the smallest caliber that is effective enough to be used against people. Some people will tell you that ANY caliber is fine. As a general rule, people that say ANY caliber is adequate don't usually have an understanding of a how a bullet stops a human being. For reference, a bullet normally stops a person by damaging vital organs and/or creating holes allowing the person's blood pressure to drop enough that the person cannot continue whatever he was doing before he got shot.

The 45 caliber pistol was used during WW2 to stop a person with one shot. They were tired of the problem of a person being shot and then getting up and returning fire. Police currently use the 9mm and 10 mm pistols. The 50 cal. is the preferred sniper weapon. As the previous answerer stated, there are many different opinions on this subject and as opinions vary, so will the answers. === === The .40 S&W is fairly popular among police agencies. Most of the groups I've trained and/or trained with use either Sig, Beretta, or Glock pistols in .40 S&W.

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