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The biggest caliber an American civilian shooter can easily get is .50 BMG. This is the round that .50 Browning machine guns use.

There are bigger calibers out there. Some elephant rifles use cartridges that fire a .60 caliber bullet. If you have the right paperwork and permits from the federal government, you can buy a small cannon and shoot 30mm or larger rounds. But among "common" rifle and pistol calibers, the .50 BMG is king of the hill.

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