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The front runner until fairly recently was the Casull .454 that produces 1900 ft lbs of muzzle pressure. However, with the release of the S&W 500 magnum x-frame .50 cal. revolver, the leader has shifted. The S&W 500 magnum produces a whopping 2600 ft lbs. muzzle pressure. No other more powerful pistol, revolver or double action (semiauto) can match it for size or power.
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