No; they married once he turned her into a vampire; early in their relationship (aprox. in 1921). They had met before; when she was 16 and he was a vampire (she never got over the experience of meeting him and he never did either because as soon as he recognized her years later; he turned her into a vampire so he won't lose her again.)
They instantly fell in love; you know once a vampire finds love; finds his soul mate for eternity: Carlisle and Esme found each other for the eternity.
He bites her... when she's about to die.
Esme =Elizabeth Reaser Carlisle = Peter facinelli
Carlisle bought Isle Esme for a present for Esme
Esme
Carlisle, for a wedding gift
She receives plain vouchers for her birthday off Carlisle and Esme
Esme Island Carlisle bought it for Esme
it is called Esme's island because it was a gift from Carlisle to his wife Esme.
Esme
Esme
Page 478 in the epilogue, no carlisle and Esme weren't there.
Carlisle Cullen's wife in the Twilight series is Esme Cullen. She is a loving and caring mother figure to the Cullen family.