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There are a few species of spider in Britain that can give a painful bite. The Raft Spider (aka Water Spider) Dysdera Crocata, Tegenaria Agrestis aka Yard Spider (bites only reported in N.America), Mouse Spider, Huntsman Spider, and the Sac Spider are the most likely to bite if mishandled. In fact most British Spiders have the ability to give a painful bite but are rarely dangerous. As far as I know, no fatalities from British spider bites have ever occurred but someone please correct this answer if I'm wrong. It should also be noted that there are a number of foreign "invaders" that have taken up residence that can give a very dangerous bite indeed, the Sydney Funnel Web spider along with scorpions have been found thriving in the London dock area. The Wasp Spider, previously only seen on the continent, is thriving in dorset and steadily spreading to other counties. Its bite though quite painful isn't thought to be dangerous.

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