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Van Leeuwenhoek made over 500 optical lenses (though they did not necessarily become 500 different microscopes) and can be said to have built at least 25 variations on his basic design of the microscope. Only nine microscopes, of the hundreds he built, remain.

The best magnification of the lenses which still exist is 256 times. It is thought that he may have been able to produce magnifications of almost twice that.

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