What happened to Lewis?

Answer 1

After the expedition, Lewis, a troubled individual, was not suited for the bureaucratic life and found himself deep amongst petty and jealous administrators. On the way to Washington to clear his name, he stopped at Fort Pickering at the Chickasaw Bluffs. Those there described him as mentally distressed. Three weeks later, he was found in his rooms with two gunshot wounds at a roadside inn at Grinder's Stand, Hohenwald, Tennessee. He died the next morning on October 11, 1809, of two gunshot wounds. Some say that they were self-inflicted, others say it was murder. Jefferson -- for as long as he'd known the man -- admitted that he had suffered from "hypochondriac afflictions."

Answer 2

I'm not sure about Lewis specifically. Could you provide more context or details so I can give you a more accurate answer?