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Do passive transport cells have flippase?
The phenomenon of multidrug resistance is correlated with the presence of a membrane protein, P-glycoprotein, which pumps a wide variety of drugs out of cells thus reducing their toxicity. This is similar to "flippase" but the mode of action is unknown. It requires energy as do all enzymes and is not a passive transport mechanism.
Flip-flop movement is shown by lipid or protein or both?
Flippase and floppase proteins are responsible for the movement of lipids in the cell membrane, allowing lipids to flip or flop between the two layers. This movement helps in maintaining the asymmetry of the lipid bilayer in cell membranes.
Which cell organelle synthesizes the lipids that make up the bulk of cell membranes?
The cell membrane is a lipid bilayer, composed of phopholipids: A glyerol molecule with two fatty-acid groups at one end and a phosphate group at the other.Phospholipids are synthesised in the cytoplasm next to the endoplasmic reticulum. The ER sythesthies the lipids, and contains enzymes that catalyse the production of phopholipids such as Glycerol-3-phosphate acyltransferase. The phospholipids produced migrate naturally to the internal face of the membrane, and flippase moves them to the outer face.
