Cholamine, or cholestyramine resin, is a prescribed medication that helps reduce cholesterol levels in the blood when used alongside changes in lifestyle such as diet and exercise. It belongs to the class of medications known as bile acid sequestrants, and works by binding to cholesterol-like substances in the intestines and preventing them from being absorbed into the body. Cholestyramine resin is also used for control of diarrhea due to Short Bowel Syndrome and to relieve itchiness associated with the partial blockage of bile ducts.