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White blood cells (WBC's), or leukocytes (also spelled "leucocytes"), are cells of the immune system defending the body against both infectious disease and foreign materials. Five[1] different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell. Leukocytes are found throughout the body, including the blood and lymphatic system.[2] The number of leukocytes in the blood is often an indicator of disease. There are normally between 4×109 and 11×109 white blood cells in a litre of blood, making up approximately 1% of blood in a healthy adult.[3] In conditions such as leukemia, the number of leukocytes is higher than normal, and in leukopenia, this number is much lower. The physical properties of leukocytes, such as volume, conductivity, and granularity, may change due to activation, the presence of immature cells, or the presence of malignant leukocytes in leukemia. Leukocyte A white blood cell protects the body against infection and fight infection when it occurs. They are bigger than red blood cells.

leukocyte[lo̅o̅′kəsīt]Etymology: Gk, leukos + kytos, cell

one of the formed elements of the circulating blood system that comprise the cells of immunity and inflammation. Five types of leukocytes are classified by the presence or absence of granules in the cytoplasm of the cell. The agranulocytes are lymphocytesand monocytes. The granulocytes are neutrophils, basophils, and eosinophils. White cells are able to squeeze through intracellular spaces by diapedesis and migrate by ameboid movements. Leukocytes measure 8 to 20 μm in diameter. Normal blood values vary from 5000 to 10,000 leukocytes per cubic millimeter. Leukocytes function as phagocytes of bacteria, fungi, and viruses; detoxifiers of toxic proteins that may result from allergic reactions and cellular injury; and immune system cells. Also spelled leucocyte. Also called white blood cell, white corpuscle. Compare erythrocyte, platelets. See also complete blood count, differential white blood cell count, leukocytosis, leukopenia. leukocytic, adj.

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