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Iron,is essential to most life forms and to normal human physiology. Iron is an integral part of many proteins and enzymes that maintain good health. n humans, Much of the iron in the body is found in red blood cells, iron is an essential component of proteins involved in oxygen transport. It is also essential for the regulation of cell growth and differentiation. Iron also is involved in producing ATP (adenosine triphosphate, the body's energy source). Extra iron is stored in the liver, bone marrow, spleen, and muscles.

Iron is abundant in Biology. Iron-proteins are found in all living organisms, ranging from the evolutionarily primitive archaea to humans. The color of blood is due to the hemoglobin, an iron-containing protein. As illustrated by hemoglobin, iron often is bound to cofactors, e.g. in hemes. The iron-sulfur clusters are pervasive and include nitrogenase, the enzymes responsible for biological nitrogen fixation. Influential theories of evolution have invoked a role for iron sulfides, iron-sulfur world theory.

Iron is a necessary trace element found in nearly all living organisms. Iron-containing enzymes and proteins, often containing heme prosthetic groups, participate in many biological oxidations and in transport. Examples of proteins found in higher organisms include hemoglobin, cytochrome (see high-valent iron), and catalase.

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