The Olfactory receptors are found in the nose. This is a poor site for its job because it is far from the ground.
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The olfactory membranes are located in the upper part of the nasal cavity and contain olfactory receptors responsible for detecting odor molecules. These receptors send signals to the brain, allowing us to perceive different smells.
Odorants bind to specific sites on the olfactory receptors, which are located on the cilia of olfactory sensory neurons in the nasal epithelium. Each olfactory receptor protein has a unique binding site that interacts with certain molecular features of the odorant, triggering a signal transduction pathway. This binding activates the receptor, leading to the generation of neural signals that are sent to the brain for odor perception.
A molecule that mimics cyclic AMP can activate olfactory receptors by binding to their target site, triggering a cascade of intracellular signals similar to the natural activation of the receptor by cyclic AMP. This can lead to the perception of a smell even in the absence of the actual odorant molecule.
They are specialised neurons in direct communication with the olfactory lobe in the brain. They differ from other neurons in having exposed receptor sites in the nasal mucosa that bind to various odoriferous chemicals. When a specific chemical binds to its appropriate receptor site, the neuron foires, releasing the chemical which may well trigger a lot more neurons. This way the brain can distinguish what smells are important. The system is poorly developed in man, but the dog has 100,000 times more receptors than we have. That's why drug sniffing dogs can find your stash so easily... Partial answer: they are found in the nose, they serve to smell and identify smells, and they play a significant role in the taste of food.
The skin is a primary site where you can find many sensory receptors. It contains various types of receptors that respond to touch, pressure, temperature, and pain. These receptors enable the body to perceive and interact with its environment, playing a crucial role in sensory perception. Other areas with sensory receptors include the eyes, ears, and taste buds, which are specialized for vision, hearing, and taste, respectively.
The chemical would be considered as odorless to that person because without the specific receptor site on the cilia of the olfactory neurons, the individual would be unable to detect or perceive the smell of the chemical.
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the active site would no longer fit into the substrate
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