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Ectrodactyly, also known as split hand-split foot malformation, primarily affects individuals in varying degrees, leading to the absence or malformation of one or more fingers or toes. It can occur as an isolated condition or as part of genetic syndromes, impacting both males and females equally. Ectrodactyly can be inherited in an autosomal dominant manner, meaning it can be passed from one generation to the next. Although it is relatively rare, it has been documented in various populations worldwide.

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3w ago

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What type of mutation is ectrodactyly?

Ectrodactyly, also known as split hand/split foot malformation, is primarily caused by genetic mutations that affect limb development. It is often associated with mutations in specific genes such as the EDA gene and can be inherited in an autosomal dominant manner. This condition results in the absence or malformation of fingers or toes, leading to characteristic "claw-like" limbs. Thus, ectrodactyly is classified as a developmental mutation affecting the morphology of the digits.


If the two middle toes on a foot are fused together is that ectrodactyly?

No, the fusion of the two middle toes is not indicative of ectrodactyly. Ectrodactyly, also known as lobster claw deformity, is a more severe condition where there is a missing or cleft hand or foot due to a congenital malformation. Fusion of toes may be due to other causes.


What diseases start with the letter e?

There are lots of diseases that start with ectodermal like Ectodermal Dysplasia Adrenal Cyst. There are also some starting with Ectopia and Ectrodactyly like Ectopia Cordis and Ectrodactyly Cleft Palate Syndrome.


Is lobster claw syndrome dominant or recessive?

Lobster claw syndrome, or Ectrodactyly, is a rare genetic condition caused by a mutation in the TP63 gene, which is inherited in an autosomal dominant pattern. This means that only one copy of the mutated gene is needed to display the syndrome.


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