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How does the development of cancer affect cyclin that regulate the cell cycle?
Wiki User
∙ 9y ago
A cancer cell can grow uncontrollably in a number of ways. One of them is to bypass the cell cycle checkpoints (G1/S, G2/M, Spindle). Mechanistically this usually occurs due to mutations of p53 or Retinoblastoma (Rb) or related-proteins.
Wiki User
∙ 12y ago
Wiki User
∙ 11y agoIn the cell cycle, the G1, S, G2 and M phase, are all triggered by chemical signals that help to signal whether cells are in need of replication for either replacement, growth or development.
One of the many ways that carcinogens affects the cell cycle is by mutating the affected cells such that these mutated cells are unresponsive and ignore the chemical signals that usually halt or start the cell cycle. By being unable to respond to these start and stop signals, the mutated and abnormal cells continue dividing uncontrollably and indefinitely.
And, as a result of uncontrollable dividing, these abnormal cells start to crowd out the neighbouring normal cells, and later forming a tumour.
Wiki User
∙ 10y agoNormally, cells have certain "boundaries" or restraints . They don't grow beyond them. When they become cancerous, they lose these restraints and grow into areas they shouldn't. This often is seen as a "piling up" of cells (tumors) and/or growth in an entirely different area (metastasis).
Wiki User
∙ 6y agoIn the most simplistic view, cancer happens when cells either "forget" to die or "forget" to quit dividing.
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How does a cell regulate the cell cycle?
The chemicals that regulate the cell cycle are called cyclins. They work by controlling the timing of the cell cycle in eukaryotic cells.
What is one of a family of closely related proteins that regulate the cell cycle in eukaryotic cells?
CYCLIN
What is cancer what causes it and how is it related to the cell cycle.?
Cancer is a disease of cells causing uncontrolled cell division. Certain proteins are a control system that regulate passage through a restriction point. This means that once the cell division cycle begins it will continue to the end.Altered regulation of expression of at least one protein (cyclin) as well as mutations of several proteins that regulate passage through the restriction point can be cancer producing.
Function of cyclin in the cell cycle?
The role is cyclins is to bind with Cdks to propel the cell through the next stage of the cell cycle as they are regulatory subunits. The cyclin part of the complex formed after binding with the cyclin-dependent protein kinase. Cyclin levels are very high especially when the cell is ready to progress to the next stage of the cell cycle, and after the cell is in the next stage, the cyclins are degraded until they are needed by the cell again.
How do mutations affect cyclins?
Cyclins regulate the timing of the cell cycle in eukaryotic cells.
What questions might scientists have asked following the discovery of cyclin?
What is the function of a cyclin?How is cyclin expression regulates?Why do protein levels of the cyclins fluctuate throughout the cell cycle?
How does a cell regulate the cell cycle?
The chemicals that regulate the cell cycle are called cyclins. They work by controlling the timing of the cell cycle in eukaryotic cells.
What is one of a family of closely related proteins that regulate the cell cycle in eukaryotic cells?
CYCLIN
What is the function of cyclin in eukaryotic cells?
The function of cyclin is to regulate the progression of the cell through the cell cycle.
What is the protein that regulate the timing of the cell cycle in eukaryotic cells known as?
CDK. Cyclin dependent kinases.
What is cancer what causes it and how is it related to the cell cycle.?
Cancer is a disease of cells causing uncontrolled cell division. Certain proteins are a control system that regulate passage through a restriction point. This means that once the cell division cycle begins it will continue to the end.Altered regulation of expression of at least one protein (cyclin) as well as mutations of several proteins that regulate passage through the restriction point can be cancer producing.
Function of cyclin in the cell cycle?
The role is cyclins is to bind with Cdks to propel the cell through the next stage of the cell cycle as they are regulatory subunits. The cyclin part of the complex formed after binding with the cyclin-dependent protein kinase. Cyclin levels are very high especially when the cell is ready to progress to the next stage of the cell cycle, and after the cell is in the next stage, the cyclins are degraded until they are needed by the cell again.
What is the function of p21 gene?
The p21 gene codes for a cyclin-dependent kinase inhibitor, which helps to regulate the cell cycle.
How do mutations affect cyclins?
Cyclins regulate the timing of the cell cycle in eukaryotic cells.
Where can you buy cyclin from?
Well dah!!! Were everyone else gets cyclin from the cyclin store!
Which cyclin forms the primary Cdkc that controls the G2 stage?
Cyclin A
What molecules control the cell cycle?
Cyclin dependent kinase
