If you mean the Lisa Smith mentioned in the link below from Urban Legends, no, she is not real.
Liza May Minnelli
Lisa Simpson's real name is Yeardley Smith
Yeardly Smith
The noun 'Ms. Smith' is a proper noun, the name of a specific person (real or fictional).
Lisa smith
Lisa Smith has written: 'Our friend Joe' -- subject(s): Lifeguards, Biography
Lisa Jane Smith
Lisa Sanman-Smith
Lisa Deschanel's birth name is Lisa Michele Smith.
She is most certainly not dead! Lisa Jane Smith is 45 years old I think.
The singer Lisa Grand's real name is Lisa-Marie Falloon
no