there may be the issue with the layer 2 protocol like hdlc or ppp is not configured or wrongly configured if the interface is serial interface.
The most likely cause for any type of line protocol being down is that a network administrator used the shutdown command on these lines to prohibit access to telnet, ssh and connection to the line con 0.
Ethernet 0/0 is down, line protocol is down
The message is something like "Serial 0/0 is up, line protocol is down". The first part refers to the physical connection (layer 1 of the OSI model), which works in this case; the second part refers to layer 2 of the OSI model (the serial networking protocol, like HDLC or PPP), which in this example doesn't work for some reason.
It is a very simple protocol used for transmission of IP datagrams across a serial line.
There is a problem with the interface at the data-link layer that prevents it from functioning properly
Serial link internet protocol..............
Serial 0/1 is up, line protocol is down
The rules for exchanging data between computers
DATA Transmission is done through SLIP (Serial Line Internet Protocol) & PPP (Point to Point Protocol) Protocols to enable computers to interact with Internet over Telephone Line.
IP, Enhanced Interior Gateway Routing Protocol (EIGRP), Serial Line Interface Protocol Frame Relay, Routing Information Protocol Version 2 (RIPv2),VLANs, Ethernet, access control lists (ACLs).
For CSLISP, the TCP header is reduced from about 20 characters to about 7. The actual data is not compressed, so you don't save very much in transmission costs per packet.
Ifconfig